Hypertonic 3% Saline in Comparison with 0.9% (Normal) Saline in Treatment of Acute Bronchiolitis

نویسندگان

  • Areege Abdul-abass Mohammed Al-Omrani Assistant Professor, CABP, Pediatric Department, College of Medicine, Al-Nahrain University, Baghdad, Iraq.
  • Asaad A Atiya Board student doctor, Pediatric Department, College of Medicine, Al-Nahrain University, Baghdad, Iraq.
چکیده مقاله:

BackgroundBronchiolitis is the commonest cause of lower respiratory tract infection in infant. Respiratory syncytial virus is the commonest cause of bronchiolitis. This study aimed to assess the efficacy of nebulized 3% hypertonic saline and salbutamol in the treatment of acute bronchiolitis in comparison with nebulized 0.9% saline and salbutamol.Materials and MethodsA prospective case second multicenter study was done at two pediatric tertiary centers at the period from 1st of December 2014 to 31 of March 2015. A total of 100 previously well infant and children of age 1-24 months with clinical diagnoses of bronchiolitis who were admitted to the hospital were included. They were divided into two groups, the study group received 4 ml of nebulized hypertonic 3% saline (for 14 days), and second group received 4 ml of nebulized normal 0.9% saline (for 14 days), each co-administer with 0.5 ml salbutamol.ResultsAll patients with acute bronchiolitis having similar baseline characteristic, mean age 4.9 + Standard deviation (SD) months, male gender constitutes 68% of the patients and the majority (67%) of the cases were below 6 months. The mean of clinical severity score at admission was 6.4 for normal saline (NS) group and 6.6 for hypertonic 3% saline (HS) group. The mean length of hospital stay of normal saline group = 4.3 + Standard deviation (SD) day and for hypertonic saline group was = 4.7 + Standard deviation (SD) day.ConclusionWe didn’t find any advantage of hypertonic 3% saline over 0.9% normal saline in terms of length of hospital stay and clinical severity score.

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hypertonic 3% saline in comparison with 0.9% (normal) saline in treatment of acute bronchiolitis

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عنوان ژورنال

دوره 5  شماره 1

صفحات  4209- 4216

تاریخ انتشار 2017-01-01

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